Jeddah, March 26, 2024, Researchers at King Faisal Specialist Hospital and Research Centre (KFSH&RC) have utilized whole-genome sequencing (WGS) technology to identify a novel bacterial species named "Stenotrophomonas Riyadhensis," as detailed in a press release from KFSH&RC. This groundbreaking discovery sheds light on the intricate dynamics between bacteria and current pharmaceuticals, paving the way for innovative therapeutic strategies. The findings represent a significant contribution to the global fight against antibiotic-resistant bacteria and underscore KFSH&RC's leading-edge research capabilities and pivotal role in advancing scientific understanding and enhancing patient care.
The identification of Riyadhensis marks a substantial advancement in combating antibiotic resistance, designing pharmaceutical interventions, and mitigating disease transmission, according to the release. It emphasizes the potential of genomic tests in revolutionizing diagnostic and treatment methodologies and deepening comprehension of bacterial resistance mechanisms, particularly in critical settings such as intensive care units (ICUs) and among immunocompromised patients.
The discovery was a result of an investigation into a suspected outbreak at the KFSH&RC ICU in 2019, initially believed to be a variant of the antibiotic-resistant Pseudomonas aeruginosa bacterium. However, through meticulous WGS analysis, researchers determined that the new bacterium did not align with the characteristics of the Pseudomonas genus but instead belonged to the Stenotrophomonas family, showcasing distinctive genetic and morphological attributes previously unseen in recognized members.
Dr. Ahmad Al Qahtani, Head of the Infectious Disease and Immunity Department at KFSH&RC, highlighted the precision and significance of WGS analysis in accurate bacterial identification and understanding resistance mechanisms. This precise approach ensures better disease outbreak management and enhances patient care outcomes.
Dr. Reem Almaghrabi, Head of Transplant Infectious Diseases at the Organ Transplant Centre of Excellence at KFSH&RC, emphasized the critical role of continuous monitoring and advanced technologies like WSG in developing faster and more reliable diagnostic methods. She stressed the importance of global scientific collaboration in combating antibiotic resistance and underlined the significance of understanding new bacterial species to effectively combat infections in modern healthcare settings.
